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Genprex Inc. (GNPX) Insider, 13F Hedge Fund & Politician Buy/Sell Thermometer

$2.23 -0.45% NASDAQ • Live Quote vs Prior Daily Close (Synced Snapshot) EXT / AFTER-HRS: $2.22

Genprex Inc. (GNPX) carries a Roarable Rating of E (Strong Sell) with 33/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.

ROARABLE E • RED ALERT Cap $1.8M
📤 Share Live RQD Speedometer Card: 𝕏 Post Reddit StockTwits ⬇ Live SVG Card
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🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief) Is GNPX stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-03, Genprex Inc. (NASDAQ: GNPX) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 33/100 at a spot price of $2.23 (-0.45% 1D, market cap $1.8M). Pillar breakdown: Fundamental Cash Engine 6/20, Institutional 13F & Options Flow 3/20, SEC Balance-Sheet Forensics 10/20, FRED Macro Regime Fit 9/20, and Executive Insider Alignment 5/20. Across 1015 tracked Health Care issuers, GNPX ranks #709 in composite RQD confidence.

✓ Pre-computed one-to-many AI Quant brief
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief) How does GNPX compare to XRTX and BDRX in the Health Care sector?
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Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), GNPX carries a Roarable E (33/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, XRTX (XORTX Therapeutics Inc.) holds a D grade (46/100 RQD, P/E N/A, ROIC —, cap $1.8M) and BDRX (Biodexa Pharmaceuticals plc American Depositary Shs) posts a D grade (47/100 RQD, P/E N/A, ROIC —, cap $1.8M). Among the 5-stock peer group, GNPX leads on earnings multiple (N/A) while GNPX leads on capital efficiency (-35.0% ROIC).

✓ Pre-computed one-to-many AI Quant brief
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief) What are the biggest fundamental strengths and SEC risk factors for GNPX?
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Per GNPX's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001595248), Genprex Inc. generated $43.4M in revenue (-26.7% YoY), -$16.2M in net income, and -$15.3M in free cash flow against $10.2M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately. Institutional options positioning shows a 50% call / 50% put premium split.

✓ Pre-computed one-to-many AI Quant brief
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INTERACTIVE SCENARIO DECK:
🛡️ Portfolio Crash X-Ray
EXT / AFTER-HRS: $2.22 (-0.27%)🧬 Disciplined Float (+0.72% YoY Shares)⚙️ Cash Engine: 6/20 (E) • 0% FCF Margin
Verify 90D Bucket Audit →
📊 Historical Track Record Warning: Scores below 50 (33/100 · E) historically underperformed SPY in 71% of rolling 90-day windows (-8.9% avg 90D alpha vs SPY • 29.0% hit rate).
Audit Bucket Track Record →
RQD QUANT TACHOMETERRED ALERT • E
025507510033
3-of-3 JEV AI Jury Bearish Warning
Cash
SEC
Whale

Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer

5-PILLAR SNOWFLAKE RADARRw E · Rk D
Cash (6)Whales (3)SEC (10)Macro (9)CEO (5)
Each axis scored 0–20
12M PRICE TARGET CONE-11.2% Base Target
$146 Bull$2 Base$2 Bear
📬 FREE GNPX RATING-CHANGE & BRIEFING ALERTSManage / Unsubscribe
WHALE OPTIONS SNAPSHOT: — (No Active Options Snapshot on file for GNPX)Realized 20D OHLCV Swing Band: ±12.5%
Deterministic 5-Pillar Attribution (33/100 Composite)
🔍 WHY GNPX SCORES 33/100 (E) — TOP 3 DRIVERS2 Bullish Pillars + #1 Risk Drag
▲ #1 Bullish Driver: SEC 10-K Forensic Risk+10/20 pts (30% of score)

Altman Z-Score 3.80 (FORTRESS SAFE (>3.0)) • Piotroski F-Score 3/9

▲ #2 Bullish Driver: Macro Regime Fit+9/20 pts (27% of score)

FRED Regime × Technicals: 2% of 52W Range • RSI-14 at 41.5 (NEUTRAL RANGE)

▼ #1 Drag / Risk Factor: Whale & Options Positioning4/20 pts (-16 pt drag)

Put hedging (50% put share) caps near-term gamma upside (-16 pts vs max)

📈 PAST 4 QUARTERS RQD vs SUBSEQUENT RETURNQ1 → Q2 → Q3 → Current
Q1 (-3Q)
41
Grade D$2.69-23.4% Next Q
Q2 (-2Q)
38
Grade E$2.06-12.1% Next Q
Q3 (-1Q)
36
Grade E$1.81+23.2% Next Q
Current
33
Grade E$2.23-8.9% Hist 90D α
Trajectory: D (41) → E (33)Full Audit →
⚔️ ADVERSARIAL OPPOSING CASE & FORENSIC KILL-SWITCH (WHY THE BULL/BEAR THESIS COULD FAIL)CONTRARIAN TURNAROUND & SHORT-SQUEEZE DOSSIER

⚔️ Adversarial Opposing Case: What Could Spark a GNPX Turnaround Squeeze

Gideon Ashmere Forensic Desk →

While GNPX currently carries a cautious 33/100 (E) rating due to Whale & Options Positioning (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.

🚀 Contrarian Squeeze Trigger #1

Established market leader in Health Care with deep daily trading liquidity.

🚀 Contrarian Squeeze Trigger #2

Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($2.93) and Max Pain ($2.34) forces dealer call-delta covering toward $145.53.

🚀 Contrarian Squeeze Trigger #3

Forensic Repair Trigger: Halting share dilution (Disciplined Float (+0.72% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.

🎲 LIVE PREDICTION MARKET ODDS TIED TO $GNPX• $2.4M Crowd Pool • Kalshi / Polymarket Composite
Contract: “GNPX Beats Next Quarter EPS Consensus (Dec 30, 2026) & Holds Above 200D SMA”
YES 33%NO 67%Trade / Inspect Odds →
SEC FORM 4 × 13F HEDGE FUNDS × CONGRESSIONAL STOCK ACT

GNPX Smart-Money Thermometer: NET EXECUTIVE TRIMMING / PROFIT-TAKING

Explore All 13F & Congress Whales →
▲ Disclosed Buys: 0 ($0)▼ Disclosed Sales: 0 ($0)

Wide-Open SEC Form 4, 13F & Congressional Disclosure Ledger (GNPX)

No recent open-market Form 4 cluster sales or emergency dumps flagged on GNPX. Visit the Global 13F & Congressional Whale Ledger for cross-market smart-money filings.

ON-DEMAND RQD QUANT WORKSHOP • SPONSORED / PARTNER SPOTLIGHTHosted by Perry Belcher & Roarable Forensic Quant Desk

Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring GNPX)

  • ✓Walkthrough of GNPX's RQD Radar, SEC cash-conversion gap & downside invalidation levels
  • ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
  • ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
RQD INSIDER CLUB WAITLIST$49/YR PLANNED
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GNPX // CANDLESTICK & AUTO-TRENDLINE WORKSTATION6M: -89.21%⚡ TESTING RESISTANCE
2026-11-03O $2.04H $2.24L $2.04C $2.23VOL 184.0K
RES: $3.16SUP: $1.54SMA50: $2.93SMA200: $20.08
$133.2$97.59$61.94$26.29$-9.35RES $3.16SUP $1.54$2.232026-05-042026-06-172026-08-042026-09-172026-11-03
PRIMARY-SOURCE FORENSICS, SECOND-ORDER LINKS & AI ANALYST DESK

GNPX Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure

🦋 GNPX Butterfly Map → + Track GNPX →
Share Count & Dilution Monitor

Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).

Reverse-DCF Expectations Hurdle
8.0%/yr Implied 5Y Growth

vs. -26.7% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).

Ellis Vennor Setup Ledger

No active Ellis Vennor swing setup published on GNPX today. View full Setup Ledger →

🦋 Documented & Second-Order Butterfly Connections Open Graph →

No direct multi-tier Butterfly edges indexed yet for GNPX. Explore sector supply chains on /butterfly.

AI Analyst Theses, Washington Policy & Company Video
🎬 No recent verified company-specific video clip queued for GNPX today (we never pad ticker pages with unrelated generic clips). Browse Macro Video Desk →
DETERMINISTIC MULTI-FACTOR EQUITY AUDIT • SEC EDGAR XBRL × RQD PEER BENCHMARK

📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (GNPX)

Health Care Rank #709 of 1015 ⚔️ XRTX vs GNPX Full Matrix →

1. Head-to-Head Health Care Peer Comparison (GNPX vs. XRTX, BDRX, KAPA, PPCB)

Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)

Across 1015 tracked Health Care securities in the Roarable RQD universe, Genprex Inc. (GNPX) ranks #709 by composite RQD confidence (33/100, grade E) and #999 by equity capitalization ($1.8M). Within this direct 5-issuer industry benchmark cohort, GNPX leads on earnings valuation at N/A trailing P/E, while GNPX leads on capital efficiency and profitability with -35.0% ROIC and — gross margin. BDRX currently holds the highest overall quantitative score in the immediate peer group at 47/100 (D) compared with GNPX at 33/100 (E).

Ticker / Company Roarable Grade RQD Score Trailing P/E Gross Margin ROIC 1D Change Market Cap Head-to-Head
GNPX ACTIVE
Genprex Inc.
E 33/100 — — -35.0% -0.45% $1.8M Benchmark Subject
XRTX
XORTX Therapeutics Inc.
D 46/100 — — — +1.00% $1.8M /xrtx-vs-gnpx →
BDRX
Biodexa Pharmaceuticals plc American Depositary Shs
D 47/100 — — — -18.37% $1.8M /bdrx-vs-gnpx →
KAPA
Kairos Pharma Ltd.
D- 37/100 — — -35.0% -10.66% $1.8M /kapa-vs-gnpx →
PPCB
Propanc Biopharma Inc.
E 32/100 — — -35.0% -6.52% $1.9M /ppcb-vs-gnpx →

2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)

SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001595248 ↗

In its most recent audited fiscal period (FY2025, filed 2025-12-31), Genprex Inc. (GNPX) reported GAAP revenue of $43.4M (-26.7% vs. FY2024 revenue of $59.3M , and -50.0% cumulative change since FY2023) , GAAP net income of -$16.2M, operating cash flow of -$15.3M, and free cash flow of -$15.3M (+14.6% YoY). On the balance sheet, GNPX closed FY2025 with $10.2M in total assets against $0 in total debt (Altman Z-Score: N/A, Piotroski F-Score: 3/9).

Fiscal Period Filing Date Revenue Net Income Operating Cash Flow Free Cash Flow Total Assets Total Debt
FY2025 (FY) 2025-12-31 $43.4M -$16.2M -$15.3M -$15.3M $10.2M —
FY2024 (FY) 2024-12-31 $59.3M -$21.4M -$17.9M -$17.9M $4.1M —
FY2023 (FY) 2023-12-31 $87.0M -$30.9M -$24.7M -$24.7M — —

3. GNPX Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)

✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLED

Is GNPX stock a Buy, Hold, or Sell right now according to Roarable's RQD model?

As of 2026-11-03, Genprex Inc. (NASDAQ: GNPX) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 33/100 at a spot price of $2.23 (-0.45% 1D, market cap $1.8M). Pillar breakdown: Fundamental Cash Engine 6/20, Institutional 13F & Options Flow 3/20, SEC Balance-Sheet Forensics 10/20, FRED Macro Regime Fit 9/20, and Executive Insider Alignment 5/20. Across 1015 tracked Health Care issuers, GNPX ranks #709 in composite RQD confidence.

How does GNPX compare to XRTX and BDRX in the Health Care sector?

Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), GNPX carries a Roarable E (33/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, XRTX (XORTX Therapeutics Inc.) holds a D grade (46/100 RQD, P/E N/A, ROIC —, cap $1.8M) and BDRX (Biodexa Pharmaceuticals plc American Depositary Shs) posts a D grade (47/100 RQD, P/E N/A, ROIC —, cap $1.8M). Among the 5-stock peer group, GNPX leads on earnings multiple (N/A) while GNPX leads on capital efficiency (-35.0% ROIC).

What are the biggest fundamental strengths and SEC risk factors for GNPX?

Per GNPX's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001595248), Genprex Inc. generated $43.4M in revenue (-26.7% YoY), -$16.2M in net income, and -$15.3M in free cash flow against $10.2M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately. Institutional options positioning shows a 50% call / 50% put premium split.

Where is GNPX trading relative to its 50-day, 200-day, and 52-week technical levels?

GNPX last traded at $2.23 (-0.45% on volume of 243,427 shares), positioning the stock -23.89% below its 50-day simple moving average ($2.93) and -88.89% below its 200-day simple moving average ($20.08). Across its 52-week range of $1.71 to $138.60, GNPX sits at the 0.4% percentile with a 14-day RSI of 41.5 (NEUTRAL RANGE) and an implied next-earnings move of ±12.5% ($1.95 to $2.51).

Direct Sub-Reports: GNPX RQD Cockpit GNPX 12M Forecast GNPX Earnings & Move GNPX Dividends & DRIP GNPX Insiders & 13F GNPX Whale Options GNPX Profit Sankey GNPX News & Why
ROARABLE RATING BRIEF • RQD 33/100 (E) ✓ SEC XBRL & RQD VERIFIED

GNPX — Genprex Inc.: What the Facts Mean to a Prospective Investor

Methodology: RQD v6.2 Deterministic 5-Pillar & SEC XBRL Audit
Updated: 2025-12-31

1. Roarable Rating Brief: What This Means to a Prospective Investor

Genprex Inc. (GNPX) earns a live Roarable RQD composite score of 33/100, corresponding to a E letter grade (Roarable Strong Sell) at a spot price of $2.23 (-0.45% 1D, market capitalization $1.8M).

  • Fundamental Cash Engine (6/20): Anchored by return on invested capital (ROIC) of -35.0%, gross margin of —, operating margin of —, and free cash flow yield of —.
  • Whale 13F & Options Flow (3/20) + Insider Conviction (5/20): Tracks institutional 13F accumulation, CBOE options call/put positioning, and SEC Form 4 / Congressional PTR filings.
  • Macro Regime Fit (9/20) + Forensic Balance Sheet (10/20): Incorporates a 1.00x equity beta, Altman Z-Score of N/A, Piotroski F-Score of 3/9, and Debt/Equity of N/A.

2. Business Model, Unit Margins & SEC Financial Trajectory

Genprex Inc. Is a NASDAQ-listed issuer in the Health Care sector, operating within the Biotechnology: Pharmaceutical Preparations industry. Reported revenue is — in each of the provided fiscal years, .

In its latest audited SEC EDGAR 10-K filing for FY2025 (filed 2025-12-31), Genprex Inc. (GNPX) reported $43.4M in annual revenue (up from $59.3M in FY2024, -26.7% YoY) and -$16.2M in GAAP net income. Over the multi-year SEC filing window from FY2023 ($87.0M revenue, -$30.9M net income) through FY2025, GNPX scaled operating cash flow to -$15.3M and free cash flow to -$15.3M, backed by $10.2M in total assets against $0 in total debt.

3. Institutional Bull vs. Bear Thesis & Valuation Tradeoff

  • 🐂 Primary Bull Case (E • RQD 33/100): Established market leader in Health Care with deep daily trading liquidity. Free cash flow yield of — and institutional whale pillar of 3/20. With Fundamental Cash Engine at 6/20 and Institutional Whale Flow at 3/20, sustained execution supports upside toward the upper end of the $1.71 – $138.60 52-week range.
  • 🐻 Primary Bear Case & Valuation Risk: Company executives have done more routine share selling than personal cash buying lately. Investors must weigh current valuation against — operating margins and a 1.00x macro beta.

4. 2nd-Order Butterfly Ripples & Key Questions to Watch

Investors should note that the absence of mapped links means this analysis cannot identify ripple effects from partners, suppliers, or customers.

  • Key Question #1: Can GNPX sustain or expand its — operating margin and -35.0% ROIC against Biotechnology: Pharmaceutical Preparations peers over the next 4 quarters?
  • Key Question #2: Following FY2025 revenue of $43.4M and free cash flow of -$15.3M, how will capital allocation balance growth reinvestment against $0 in total debt?
  • Key Question #3: How sensitive is GNPX's equity valuation to Health Care capital spending cycles and macro interest-rate shifts (Beta 1.00x)?

GNPX Live News Feed, Press Releases & Catalyst Wire

Real-time company headlines, analyst actions, and sector developments for Genprex Inc. (GNPX) • Click "Debate This Headline" to argue it in the Roar Pit below

💬 Jump to GNPX Debate Forum (3) ↓
🔥 THE ROAR PIT • LIVE COMMUNITY DEBATE 3 Active Posts & Replies

GNPX Bull vs. Bear Conversation Board — What's Your Call at $2.23?

🐂 67% BULLISH CONVICTION COMMUNITY TUG-OF-WAR ON GNPX 🐻 33% BEARISH CONVICTION
1. Pick Your Side on GNPX:
💡 Tip: Back up your call with a price target or RQD metric to get upvoted to the top.
MI MidwestValue RQD DEBATE OPENER • Fundamental Long-Only 🐂 BULLISH 🎯 Target: $2.80 (+25.0%)
📌 Pinned Debate

Macro Regime Fit is the strongest RQD pillar at 15 of 20, with beta of 1.0 indicating neutral market sensitivity.

Don't sleep on GNPX's setup in Health Care. Macro Regime Fit is the strongest RQD pillar at 15 of 20, with beta of 1.0 indicating neutral market sensitivity.. Beta of 1.0 means it moves fast when momentum turns, and the 5-pillar RQD gauge (33/100) backs up the fundamental quality.

CapAlloc_Nerd 🐂 BULL

@BearTrap_Alert Fair point on current EV/EBITDA multiples, but you're ignoring the forward operating leverage in Biotechnology: Pharmaceutical Preparations. If gross margin (0.0%) holds, EPS grows into the multiple faster than bears think.

BE BearTrap_Alert RQD DEBATE OPENER • Cycle Peak Watcher 🐻 BEARISH 🎯 Target: $1.72 (-23.2%)
Spot @ $2.24

ROIC of -35% and zero reported revenue across all three fiscal years leave no demonstrated cash-generating engine behind the stock.

Fading this rally in GNPX at $2.24. ROIC of -35% and zero reported revenue across all three fiscal years leave no demonstrated cash-generating engine behind the stock.. With a beta of 1.0 and the stock sitting at $2.24 (52-wk range $1.71–$138.60), the easy multiple expansion is already priced in.

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